Instructions And Frequently Asked Questions

Step-By-Step Instructions

Use Plexaderm on clean, dry skin and before applying any makeup.

1. Wash and Dry Skin
2. Start with a small amount of serum on your fingertip (about half the size of a pea).
3. Gently apply a thin, even layer to targeted areas, being careful to avoid contact with eyes.
4. Allow Plexaderm® Rapid Reduction Serum to set and dry (10 minutes for optimal results).

We highly recommend using Plexaderm 100% Hyaluronic Moisturizer™ (sold separately) as part of your daily routine, whether it be before bedtime and/or in the morning.

To achieve maximum Plexaderm® effects, do not apply Plexaderm 100% Hyaluronic Moisturizer™—or any moisturizer—to areas of skin where Plexaderm® is to be applied as this may lessen product effectiveness. If you don’t get the desired results, a second application may be applied to maximize results.

-Using too much serum may leave a white line around the application area. If this happens gently tap edge with a damp
-Some users see the best results after a second application of Rapid Reduction Serum.

-If the first application does not show noticeable results after 5 minutes simply repeat steps 2-4.

See the ingredients of Plexaderm Rapid Reduction Serum.

Quick Tips 

Tip: If you get a white film on your skin, you've used too much.
Tip: Avoid use of oil-based products as they may deactivate the effects of the Plexaderm. We recommend using our Hyaluronic Moisturizer at night. It is water-based and helps to re-hydrate your skin while you sleep.

Common Questions
Over the past year we carefully listened to our customers concerns with the pump, and we listened. We worked tirelessly with our manufacturing partners to develop this amazing new resealable tube packaging that is incredibly easy to use, will not jam or clog, and ensures your product stays fresh between uses.
In order to deliver the best possible customer experience, we have decided to discontinue the Plexaderm Rapid Reduction Serum pump. You can still experience all the same great results using our resealable tube packaging.
Yes you can! However, to maintain maximum results we do suggest using dry or powdered makeup anywhere you have applied the Rapid Reduction Serum.
The Plex-Perfect Daily Moisturizer was developed specifically to be used with our Plexaderm Rapid Reduction Serum. The oil-free formula works to thoroughly hydrate the skin without impacting the amazing skin-tightening effects of the Serum. If you are using your own moisturizer it should be oil-free and applied at least 10-20 minutes prior to the Rapid Reduction Serum, but results can vary from product to product.
Plexaderm lasts for up to 10 hours or until you wash it off at the end of the day. Extreme sweat, certain oils and very oily skin will shorten its effects; however, if you apply it to a clean dry face, allow for the proper time to dry and set (5-10 Minutes), you will get effects that lasts for many hours with impressive results.
Purified Water (Aqua), Propylene Glycol, Sodium Silicate, Magnesium Aluminum Silicate, Acetyl Hexapeptide-8, Hydrolyzed Rice Protein, Soluble Collagen, Cellulose Gum, Xanthan Gum, Titanium Dioxide, CI 77491, CI 77492, Phenoxyethanol, Ethylhexylglycerin.
You can remove excess Plexaderm® by using a damp washcloth, and dabbing gently onto the affected areas.
Results vary by individual, but you can expect to see a significant difference in the texture, tone and appearance of your skin after just one use of the Rapid Reduction Serum!
Yes! Once Plexaderm® is applied, use a blow dryer on the lowest temperature setting.
Additional Plexaderm products can be purchased by contacting our sales department at (800) 673-2201 or by visiting
As we age, the tissue and skin that holds in fat below our eyes can weaken. When the tissue weakens, fat can push forward giving you unsightly bags below your eyes. What can make it look even worse is that fat can cast a shadow from light above, making you look tired, older and just worn out.
Plexaderm has been used by thousands of people without any significant side effects. If you experience a reaction of any type, please call customer service and let us know.